Results: Huntington Disease

Results from Abstracts

Pick one of the followings

*Some genes may be words of complete meaning. In any case, if present, they are relevant key words.

Legend:

***	p-value <= 0.001
**	p-value <= 0.01
*	p-value <= 0.05
n.s.	not significant

Top Ranked Genes, Molecules or Short Names*

Htt ***
Bdnf **
Hace1 *
Slc1a2 *
Ctnna2 *
Taf1 *
Mfn1 *
Ogg1 *
Adcy5 *
Pgd *
Tfeb *
Msn *
Rock1 *
Ran *
Msh3 n.s.
Tom1 n.s.
Bag3 n.s.
Snap25 n.s.
Psd n.s.
Grin2a n.s.
Pgc n.s.
Npy n.s.
Mtr n.s.
Dmpk n.s.
Tbp n.s.
Hap1 n.s.
Casp6 n.s.
Tollip n.s.
Atxn3 n.s.
Ppargc1a n.s.
Hspb8 n.s.
Prnp n.s.
Lpo n.s.
Hsf1 n.s.
Atxn2 n.s.
Jph3 n.s.
Ido1 n.s.
Pde10a n.s.
C9orf72 n.s.
Proc n.s.
Afm n.s.
Gapdh n.s.
Atn1 n.s.
Mri n.s.
Aes n.s.
Atxn7 n.s.
Vps13a n.s.
Rest n.s.
Cacna1a n.s.
Igf1 n.s.
Ttr n.s.
Npy2r n.s.
Npy5r n.s.
Npy1r n.s.
Pdk2 n.s.
Yod1 n.s.
Bop n.s.
Ltn1 n.s.
Acbd3 n.s.
Hdac3 n.s.
Gpr18 n.s.
Sim1 n.s.
Ppp1r1b n.s.
Nfya n.s.
Drd1 n.s.
Plk5 n.s.
Calcoco2 n.s.
Mapt n.s.
Hsh2d n.s.
Tnfrsf10c n.s.
Rps27l n.s.
Tnfrsf10b n.s.
Zfp30 n.s.
Ddb2 n.s.
Zfp57 n.s.
Plk2 n.s.
Prkcq n.s.
Tnfrsf10d n.s.
Mapk11 n.s.
Pin1 n.s.
Hipk2 n.s.
Fxn n.s.
Hdac7 n.s.
Dnajb6 n.s.
Abcg4 n.s.
Itch n.s.
Dnajc5 n.s.
Kcnma1 n.s.
Dlg4 n.s.
Fan1 n.s.
Por n.s.
Kmo n.s.
Hypk n.s.
Dnm1 n.s.
Bag1 n.s.
Rrs1 n.s.
Rab11a n.s.
Hdac1 n.s.
Rack1 n.s.
Prkra n.s.

Top Ranked Key Phrases

S disease rating scale uhdrs ***
Brain derived neurotrophic factor bdnf ***
S disease rating scale ***
Amyotrophic lateral sclerosis als ***
Fatal neurodegenerative disorder caused ***
Including huntington disease hd ***
Huntington disease like 2 hdl2 ***
Amyotrophic lateral sclerosis ***
Fragile x syndrome ***
Expanded cag repeat ***
Wild type littermates ***
Wild type htt ***
Cag repeat length ***
Progressive neurodegenerative disorder ***
Cag repeat expansion ***
Mutant huntingtin protein ***
Hd mouse model ***
Huntingtin htt protein ***
Huntingtin protein htt ***
Mutant huntingtin mhtt ***
Neurodegenerative disorder caused ***
Huntingtin gene htt ***
Huntingtin htt gene ***
Hd mouse models ***
S disease hd ***
Yac128 mouse model ***
S disease ad ***
Total functional capacity ***
S disease pd ***
Including huntington disease **
Huntington disease hd **
Yac128 hd mice **
Predict hd study **
Cag repeat number **
Predictive genetic testing **
Alzheimer disease ad **
Parkinson disease pd **
Present study was **
Autosomal dominant **
Huntington disease patients **
Wild type *
Cross sectional *
Cag repeat *
White matter *
Repeat length *
Inclusion bodies *
Neurodegenerative disorder *
Polyglutamine tract *
Pre hd *
Movement disorder *
Terminal fragments *
Er stress *
Juvenile hd *
Human hd *
Neurotrophic factors *
Mutant huntingtin *
Mutant htt *
Hd gene *
Striatal atrophy *
Multiple sclerosis *
Huntingtin protein *
Htt protein *
Mutant cells *
Eye movements n.s.
Huntingtin gene n.s.
Htt gene n.s.
Cerebrospinal fluid n.s.
Striatal volume n.s.
Hd cells n.s.
Mouse model n.s.
Cag repeats n.s.
Mcleod syndrome n.s.
Cag expansion n.s.
Neurodegenerative disease n.s.
Human disease n.s.
Human genome n.s.
Globus pallidus n.s.
Glial cells n.s.
Early hd n.s.
Huntingtin htt n.s.
Mouse brain n.s.
Neuronal cells n.s.
Significantly reduced n.s.
Involuntary movements n.s.
Hd mutation n.s.
Significantly higher n.s.
Basal ganglia n.s.
Ethyl epa n.s.
Polyq diseases n.s.
Hd models n.s.
Hd mice n.s.
Polyglutamine expansion n.s.
Mouse models n.s.
Physical activity n.s.
Was associated n.s.
Study was n.s.
Oxidative damage n.s.
Striatal neurons n.s.
Adverse events n.s.
S disease n.s.

Top Ranked Mesh Terms

Gene expression regulation ***
Magnetic resonance imaging ***
Peptides ***
Models biological ***
Mutation ***
Severity of illness index ***
Genetic predisposition to disease ***
Neurodegenerative diseases ***
Signal transduction ***
Diagnosis ***
Genotype ***
Quality of life ***
Corpus striatum ***
Neuroprotective agents ***
Age of onset ***
Rats ***
Pathology ***
Pedigree ***
Aged 80 and over ***
Alleles ***
Aged ***
Chemistry ***
Reproducibility of results ***
Disease models animal ***
Cell line ***
Young adult ***
Cognition ***
Disease progression ***
Animals ***
Physiology ***
Adolescent ***
Cognition disorders ***
Drug therapy ***
Motor activity ***
Psychology ***
Mice ***
Humans ***
Brain ***
Oxidative stress ***
Pharmacology ***
Adult ***
Hek293 cells ***
Nerve tissue proteins ***
Cell death ***
Case-control studies ***
Autophagy ***
Phenotype ***
Female ***
Trinucleotide repeats ***
Male ***
Diagnostic imaging ***
Longitudinal studies ***
Neurons ***
Cerebral cortex ***
Mice inbred c57bl ***
Genetic counseling ***
Trinucleotide repeat expansion ***
Movement disorders ***
Metabolism ***
Mutant proteins ***
Biomarkers ***
Huntington disease ***
Methods ***
Epidemiology ***
Huntingtin protein ***
Genetic testing ***
Protein binding ***
Middle aged ***
Cells cultured ***
Neuropsychological tests ***
Nuclear proteins ***
Prodromal symptoms ***
Genetics ***
Surveys and questionnaires ***
Mice transgenic ***
Cohort studies ***
Aging ***
Risk factors ***
Chorea ***
Protein structure tertiary ***
Phosphorylation ***
Child ***
Mitochondria ***
Atrophy ***
Analysis of variance ***
Retrospective studies ***
Treatment outcome ***
Nerve degeneration ***
Protein folding ***
Brain-derived neurotrophic factor ***
Predictive value of tests ***
Parkinson disease ***
Behavior animal ***
Cross-sectional studies **
Psychomotor performance **
Depression **
Mice knockout **
Time factors **
Transcription factors **
Age factors **

Top Ranked Mesh Terms (Symptoms)

Disease progression ***
Prodromal symptoms ***
Genetic predisposition to disease ***
Atrophy ***
Nerve degeneration ***
Chorea ***
Body weight **
Genomic instability *
Memory disorders *
Protein aggregation pathological *
Dyskinesias *
Hypokinesia *
Diseases in twins *
Olfaction disorders *
Speech disorders *
Anticipation genetic *
Death sudden *
Pain *
Muscle rigidity *
Cerebellar ataxia *
Tardive dyskinesia *
Gait disorders neurologic *
Plaque amyloid *
Ataxia *
Tics *
Necrosis *
Dystonia *
Rare diseases *
Tremor n.s.
Microsatellite instability n.s.
Syndrome n.s.
Supranuclear palsy progressive n.s.
Seizures n.s.
Gliosis n.s.
Weight loss n.s.
Asymptomatic diseases n.s.
Hyperkinesis n.s.
Sleep wake disorders n.s.
Postmortem changes n.s.
Psychomotor agitation n.s.
Chronic disease n.s.
Psychomotor disorders n.s.
Ophthalmoplegia n.s.
Myoclonus n.s.
Inflammation n.s.
Headache n.s.
Cadaver n.s.
Paraplegia n.s.
Late onset disorders n.s.
Fasciculation n.s.
Communication disorders n.s.
Dysarthria n.s.
Catatonia n.s.
Chromosome fragility n.s.
Death n.s.
Hypothermia n.s.
Torticollis n.s.
Dyskinesia drug-induced n.s.
Ventricular remodeling n.s.
Language disorders n.s.
Alpha 1-antitrypsin deficiency n.s.
Language development disorders n.s.
Hypertrophy left ventricular n.s.
Dysphonia n.s.
Granuloma annulare n.s.
Cell transformation viral n.s.
Paralysis n.s.
Asthenia n.s.
Channelopathies n.s.
Mobility limitation n.s.
Agnosia n.s.
Dizziness n.s.
Apraxias n.s.
Dysmenorrhea n.s.
Disease susceptibility n.s.
Hearing loss n.s.
Uniparental disomy n.s.
Perceptual disorders n.s.
Fever n.s.
Sensation disorders n.s.
Hypoxia n.s.
Aneuploidy n.s.
Chromosome aberrations n.s.
Translocation genetic n.s.
Neoplasm metastasis n.s.
Fatigue n.s.
Weight gain n.s.

Results for: Huntington Disease

Results from Abstracts

KEGG Pathways

Gene Ontology Biological Processes